Publications

Systematic analysis of nonprogrammed frameshift suppression in E. coli via translational tiling proteomics.
Springstein, B. L.; Paulo, J. A.; Park, H.; Henry, K.; Fleming, E.; Feder, Z.; Harper, J. W.*; Hochschild, A.*
Proc. Natl. Acad. Sci. USA 2024, 121 (6), e2317453121. (IF: 11.1)

Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin–p65 interaction.
Yim, J.; Lee, J.; Yi, S.; Koo, J. Y.; Oh, S.; Park, H.; Kim, S. S.; Bae, M. A.; Park, J.*; Park, S. B.*
Exp. Mol. Med. 2022. (IF: 12.172)

Spatial Snapshots of Amyloid Precursor Protein Intramembrane Processing via Early Endosome Proteomics.
Park, H.; Yu, Q.; Hundley, F. V.; Overmyer, K.; Serrano, L.; Paulo, J. A.; Swarup, S.; Coon, J. J.; Gygi, S. P.; Harper, J. W.*
Nat. Commun. 2022, 13. (IF: 17.694)

Recent advances in identifying protein targets in drug discovery.
Ha, J#.; Park, H#.; Park, J.*; Park, S. B.*  # Equal contribution
Cell Chem. Biol. 2021, 28 (3), 394-423. (IF: 8.116)

Phenotypic discovery of an anti-virulence agent against Vibrio vulnificus via modulation of quorum-sensing regulator SmcR.
Kim, S. M.#; Park, J.#; Kim, M. S.; Song, H.; Jo, A.; Park, H.; Kim, T. S.; Choi, S. H.*; Park, S. B.*  # Equal contribution
ACS Infect. Dis. 2020, 6 (11), 3076-3082. (IF: 5.084)

Phenotype-based discovery of a HeLa-specific cytotoxic molecule that downregulates HPV-mediated signaling pathways via oxidative damage.
Lee, S.#; Cho, W.#; Hong, S.; Yi, S.; Kim, H.; Baek, S. Y.; Park, H.; Jung, J.; Shin, Y. K.; Park, S. B.*  # Equal contribution
Org. Biomol. Chem. 2019, 17 (31), 7388-7397. (IF: 3.876)

Label-free target identification in drug discovery via phenotypic screening.
Park, H.; Ha, J.; Park, S. B.*
Curr. Opin. Chem. Biol. 2019, 50, 66-72. (IF: 9.689)

Label-free target identification reveals oxidative DNA damage as the mechanism of selective cytotoxic agent. (Selected as the Front Cover Article)
Park, H.; Park, S. B.*
Chem. Sci. 2019, 10 (12), 3449-3458. (IF: 9.346)

Label-free target identification using in-gel fluorescence difference via thermal stability shift.
Park, H.; Ha, J.; Koo, J. Y.; Park, J.; Park, S. B.*
Chem. Sci. 2017, 8 (2), 1127-1133. (IF: 9.063)

Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells.
Park, H.#; Koo, J. Y.#; Srikanth, Y. V. V.; Oh, S.; Lee, J.; Park, J.*; Park, S. B.*  # Equal contribution
Chem. Commun. 2016, 52 (34), 5828-5831. (IF: 6.222)

Discovery of a small-molecule inhibitor of protein–microRNA interaction using binding assay with a site-specifically labeled Lin28.
Lim, D.; Byun, W. G.; Koo, J. Y.; Park, H.; Park, S. B.*
J. Am. Chem. Soc. 2016, 138 (41), 13630-13638. (IF: 15.419)